A study published in Nature – International Journal of Science confirms that individuals with extra copies of chromosome 21, as found in individuals with Down syndrome, have genes that block certain types of cancer growth. This may have far-reaching implications in the therapies we use to treat cancer.

Most types of cancer are rare in individuals with Down syndrome and they are shown to have a far lower mortality rate than those in the general population.

Late cancer researcher Judah Folkman, MD, who founded the Vascular Biology Program at Children’s Hospital Boston, first proposed that these individuals may benefit from an extra gene that blocks angiogenesis (or the development of certain blood vessels that create an environment for cancer growth), as they are also less likely to develop other diseases related to this same type of growth, such as macular degeneration.

This study confirms Dr. Folkman’s theory and provides new insight for the development of specific, targeted treatments. The research proved that the same cells in both mice and humans followed the same type of angiogenesis suppression, meaning they might point to a new and exciting type of cancer therapy.

NACD has been dedicated over the last several decades to addressing issues that impact children and adults with Down syndrome. We seek to change public opinion as well as the opinions of parents and professionals about their potential. Studies like this just confirm what we have always known—that these individuals have many undiscovered gifts to offer and uncover.

References

1. Kwan-Hyuck Baek, Alexander Zaslavsky, Ryan C. Lynch, Carmella Britt, Yoshiaki Okada, Richard J. Siarey, M. William Lensch, In-Hyun Park, Sam S. Yoon, Takashi Minami, Julie R. Korenberg, Judah Folkman, George Q. Daley, William C. Aird, Zygmunt Galdzicki & Sandra Ryeom. Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature, 2009; DOI: 10.1038/nature08062
2. Children’s Hospital Boston. “Why Do People With Down Syndrome Have Less Cancer? Research In Mice And Human Stem Cells Suggests New Therapeutic Targets.” ScienceDaily. www.sciencedaily.com/releases/2009/05/090520140359.htm (accessed June 18, 2018).

The post NACD Science Corner Vol. 14 – Why Do People with Down Syndrome Have Less Cancer? appeared first on NACD International | The National Association for Child Development.

It might not be that shocking to find homeschoolers get more sleep than their public school peers, but a new study which featured 2,600 adolescents around the nation found homeschoolers get on average 90 minutes more sleep per night!

Just to put that into perspective, 90 minutes a night over the course of a 5-day school week equates to 1 entire night of extra sleep. Ninety minutes is also the length of an entire extra REM cycle, which means homeschooled students have a huge advantage when it comes to consolidating the information learned the previous day into long-term memory, recovering from the physical and mental demands of the previous day, and having increased vitality and focus to face the next day head-on. It has long been known that when puberty begins, the internal biological clock normally has a sleep-phase delay in which adolescents naturally go to bed later at night, and consequently, wake up later in the morning. Yet, in spite of this understanding, most middle schools and high schools start school even earlier in the day compared to elementary. It’s no wonder only 24.5% of public school adolescents are meeting their daily sleep requirement! Homeschooling simply gives the flexibility in scheduling to allow the child to wake up not when the alarm clock goes off, but when the biological clock goes off. To read more about NACD’s programs for homeschoolers click here.

Source:

Hughes, T. (2013, March 15). Study: Home-schoolers better rested than other students. Retrieved from http://www.usatoday.com/story/news/na5on/2013/03/14/home-school-sleep-study/1986781/ Dawson, P. (2005). Sleep and Adolescents. National Association of School Psychologists.

The post Science Corner Vol. 3 – The Sleep Advantage of Homeschooling: Scientifically Verified appeared first on NACD International | The National Association for Child Development.